One drop can be beneficial, one swig can be deadly: tetrahydrozoline intoxication.
نویسندگان
چکیده
Tetrahydrozoline is a commonly used imidazoline derivative with serious side effects and toxicity, particularly in small children. A one-year-old boy was admitted to the emergency department (ED) after he accidentally ingested about half a bottle of nasal decongestant solution containing tetrahydrozoline. He was unconscious, hypothermic and bradycardic on presentation. His respiration was irregular and superficial, and blood pressure was borderline hypotensive. His skin was pale and cold. Atropine was administered twice for symptomatic bradycardia, and the child was transferred to the pediatric intensive care unit (PICU). During the 12th hour of observation, vital signs returned to normal and there was no need for mechanical ventilation. Although suitable room temperature with passive warming was applied, hypothermia continued for approximately 24 hours. The patient was discharged on the second day of admission. There were no complaints one week later, and the physical examination was normal. We report a case of accidental tetrahydrozoline intoxication with life-threatening events accompanying hypothermia in a small infant.
منابع مشابه
I-13: Blastocyst Culture and Freezing
It should now be beyond doubt that blastocyst culture results in better pregnancy rate (PR). This calls for fewer embryos to be transferred, and indeed blastocyst culture is of most value when the intention is to put back one embryo at a time. The PR with one top-grade blastocyst is 45-65% in different studies. If two top-grade blastocysts are transferred, the PR usually does not differ, but th...
متن کاملA Foreign-Function Interface Generator for occam-pi
occam-pi is a programming language based on the CSP process algebra and the pi-calculus, and has a powerful syntax for expressing concurrency. occam-pi does not however, come with interfaces to a broad range of standard libraries (such as those used for graphics or mathematics). Programmers wishing to use these must write their own wrappers using occam-pi’s foreign function interface, which can...
متن کاملA successful management of Aluminum Phosphide intoxication
Background: Aluminum Phosphide or rice tablet is one of the most common pesticides which leads to accidental or intentional acute intoxication and finally death. In this paper, we describe a successful management of intoxication with rice tablet in a young girl. Case presentation: A 14-year-old girl was admitted due to consumption of rice tablet. Gastric washing with two vials of sodium bicarbo...
متن کاملDevelopment and validation of a reversed-phase HPLC method for analysis of tetrahydrozoline hydrochloride in eye drop formulations
A simple, precise, accurate, and stability-indicating method is developed and validated for analysis of tetrahydrozoline hydrochloride in eye drop formulations. Separation was achieved on a reversed-phase C8 column (125 mm×4.6 mm i.d., 5 μm) using a mobile phase consisting of acetonitrile/phosphate buffer of pH 3.0 (20:80, v/v) at a flow rate of 1.0 mL/min and UV detection at 240 nm. This metho...
متن کاملWrappers for ADOL-C in scripting languages using SWIG
R is a language and environment for statistical computing and graphics [1]. It currently is widely used in statistics and data mining. To obtain derivatives in R, one can use several non-native approaches, including the TMB system [2] and Ryacas [3]. However, none of these options support the di↵erentiation of functions expressed as R programs, as would an algorithmic di↵erentiation (AD) tool f...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- The Turkish journal of pediatrics
دوره 54 6 شماره
صفحات -
تاریخ انتشار 2012